Gene Report

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Basic Info

Approved Symbol	NUDCD1
Symbol Alias	CML66, FLJ14991
Approved Name	NudC domain containing 1
Location	8q23
Position	chr8:109240919-109334385, -1
External Links	HGNC: 24306 Entrez Gene: 84955 Ensembl: ENSG00000120526 UCSC: uc003ynb.4
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs2980619, rs4129682, rs4734194, rs6469241	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005634	nucleus	cellular component	IDA	283

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0002376	immune system process	biological process	IEA	3
GO:0005737	cytoplasm	cellular component	IDA	322
GO:0005654	nucleoplasm	cellular component	IDA	163
GO:0005515	protein binding	molecular function	IPI[25036637]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 18)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs2980619	chr8:109289818 - 109289818(1)	3_prime_UTR_variant; missense_variant; NMD_transcript_variant	1(0/1/0)
rs4734194	chr8:109138442 - 109138442(1)		1(0/1/0)
rs4129682	chr8:109109910 - 109109910(1)	intron_variant	1(0/1/0)
rs6469241	chr8:109141703 - 109141703(1)		1(0/1/0)

rs_ID	Location	Functional Annotation
rs2926214	chr8:109239769 - 109239769(1)	downstream_gene_variant
rs1531298	chr8:109243861 - 109243861(1)	intron_variant; NMD_transcript_variant
rs2980589	chr8:109246864 - 109246864(1)	intron_variant; NMD_transcript_variant
rs2980591	chr8:109247307 - 109247307(1)	intron_variant; NMD_transcript_variant
rs2125513	chr8:109269251 - 109269251(1)	intron_variant; NMD_transcript_variant
rs2926208	chr8:109255674 - 109255674(1)	intron_variant; NMD_transcript_variant
rs1993594	chr8:109277807 - 109277807(1)	intron_variant; NMD_transcript_variant
rs2980606	chr8:109273099 - 109273099(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant
rs2980623	chr8:109296099 - 109296099(1)	intron_variant; NMD_transcript_variant; upstream_gene_variant
rs2980620	chr8:109290191 - 109290191(1)	intron_variant; NMD_transcript_variant
rs2168964	chr8:109299409 - 109299409(1)	intron_variant; NMD_transcript_variant; non_coding_transcript_variant
rs2926265	chr8:109298251 - 109298251(1)	intron_variant; NMD_transcript_variant; upstream_gene_variant
rs2926244	chr8:109333032 - 109333032(1)	intron_variant; NMD_transcript_variant; upstream_gene_variant
rs2980636	chr8:109324443 - 109324443(1)	intron_variant; NMD_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 8	chr8:0-145138636	3 (0/3/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr8:109240919..109334385 View in gBrowse