Gene Report

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Basic Info

Approved Symbol	GLDN
Previous Symbol	COLM
Symbol Alias	CRG-L2, CLOM, colmedin, UNC-112
Approved Name	gliomedin
Previous Name	collomin
Location	15q15.3
Position	chr15:51341629-51408013, 1
External Links	HGNC: 29514 Entrez Gene: 342035 Ensembl: ENSG00000186417 UCSC: uc002aba.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Noor A., 2014		Selected stringent CNV related to this gene is validated by qPCR from BD case data.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005886	plasma membrane	cellular component	IEA	360
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005615	extracellular space	cellular component	IEA	85
GO:0034113	heterotypic cell-cell adhesion	biological process	IEA	1
GO:0045162	clustering of voltage-gated sodium channels	biological process	IEA	1
GO:0005581	collagen trimer	cellular component	IEA	4
GO:0032528	microvillus organization	biological process	IEA	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	molecular function	IEA	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Abdul Noor[2014]_18	chr15:49418771-49482945 (NCBI Build 36/hg18)	64000	15q21.2	deletion

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
15q15.1-21.2	chr15:39800000-52600000	1 (0/0/1)
15q21	chr15:44500000-58800000	1 (0/1/0)
Chr 15	chr15:0-101991189	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr15:51341629..51408013 View in gBrowse