Gene Report

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Basic Info

Approved Symbol	FSTL5
Symbol Alias	DKFZp566D234, KIAA1263
Approved Name	follistatin-like 5
Location	4q32.3
Position	chr4:161383897-162164035, -1
External Links	HGNC: 21386 Entrez Gene: 56884 Ensembl: ENSG00000168843 UCSC: uc003iqh.4
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Sklar, P.,2011	SNP: rs17395886	Suggestive association was found.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005509	calcium ion binding	molecular function	IEA	50

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005576	extracellular region	cellular component	IEA	97

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs17395886	chr4:161358233 - 161358233(1)		1(0/0/1)

rs_ID	Literature-origin SNPs with LD	Location	Functional Annotation
rs4691753		chr4:161396834 - 161396834(1)	intron_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 4	chr4:0-190214555	3 (0/3/0)
4q31.22-34.1	chr4:145900000-175400000	1 (0/0/1)
4q32	chr4:154600000-169200000	3 (0/0/3)
4q31-35	chr4:138500000-190214555	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr4:161383897..162164035 View in gBrowse