Gene Report

Approved Symbol	CSMD1
Symbol Alias	KIAA1890, PPP1R24
Approved Name	CUB and Sushi multiple domains 1
Name Alias	protein phosphatase 1, regulatory subunit 24
Location	8p23.2
Position	chr8:2935353-4994972, -1
External Links	HGNC: 14026 Entrez Gene: 64478 Ensembl: ENSG00000183117 UCSC: uc022aqr.1
No. of Studies	4 (Positive: 2; Negative: 1; trend: 1)
Overlap with SZ?	NO
Overlap with MDD?	NO

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs10089209, rs1154037, rs12056919, rs17063147, rs922790	These include SNP rs1154037 in CSMD1, for which the intronic SNP rs4875310 was suggestive significant in the Sklar et al. 2008 study (p = 3.74×10-5).	Negative	Comment on Study
Hattori, E.,2009	SNP: rs10503227	After the two-stage analysis, markers in this gene remained nominally significant (allelic P<0.05) with the same allele being consistently over-represented in both the first and the follow-up stages.	Positive	Comment on Study
Johnson, C.,2009		Monte-Carlo Simulation P-value = 0.0011. One of Genes That Harbor Overlapping Clusters of 4 Nominally Positive SNPs Whose Allele Frequencies Distinguish Individuals With Bipolar Disorder From Controls With P<0.05 Nominal Significance From at Least Three of the Four Samples in This Analysis	Positive	Comment on Study
Jamain, S., 2014	SNP: rs1504772	It showed nominal evidence for association with BD.	Trend	Comment on Study

Region: chr8:2935353..4994972 View in gBrowse