Gene Report

Basic Info
Approved Symbol CHRNA6
Approved Name cholinergic receptor, nicotinic, alpha 6 (neuronal)
Previous Name cholinergic receptor, nicotinic, alpha polypeptide 6
Name Alias acetylcholine receptor, nicotinic, alpha 6 (neuronal)
Location 8p22
Position chr8:42752620-42796392, -1
External Links HGNC: 15963
Entrez Gene: 8973
Ensembl: ENSG00000147434
UCSC: uc003xpj.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2007 SNP: rs10107450 no evidence of interaction among these 19 cholinergic genes was found by Allelic Association, Haploview Tests, FITF analysis and FDR correction Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 3)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 10)

Literature-origin SNPs (count: 1)

LD-proxies (count: 9)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr8:42752620..42796392 View in gBrowse
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