Gene Report

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Basic Info

Approved Symbol	ABCC12
Symbol Alias	MRP9
Approved Name	ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Location	16q12.1
Position	chr16:48082973-48156018, -1
External Links	HGNC: 14640 Entrez Gene: 94160 Ensembl: ENSG00000140798 UCSC: uc002efc.1
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Xu, W., 2014	SNP: rs13331266	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0055085	transmembrane transport	biological process	IEA	77
GO:0005739	mitochondrion	cellular component	IEA	75
GO:0005524	ATP binding	molecular function	IEA	118
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	molecular function	IEA	4
GO:0008152	metabolic process	biological process	IEA	50

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in BDgene	Brief Description
hsa02010	ABC transporters	5

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs13331266	chr16:48128160 - 48128160(1)	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 16	chr16:0-90338345	5 (1/3/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr16:48082973..48156018 View in gBrowse