BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Basic Info

Name	TPH1 intron 7 218A/C
Type	SNP
Location	intron 7
Related Gene	TPH1
No. of Study	2 (Positive: 0; Negative 2; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kunugi, H.,1999(a)	218A/C		Chi square tests:genotype,chi square = 3.5, df = 2, p = 0.17;allele,chi square = 3.5, df = 1, p = 0.06	No significant differences were found in bipolar groups.	Negative
McQuillin, A.,1999	A218C		chi square tests:all P-value >0.05	No significant differences were found in bipolar groups.	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Kunugi, H.,1999(a)	Chi square tests:genotype,chi square = 2.2, df = 2, p = 0.34;allele,chi square = 0.9, df = 1, p = 0.35	No significant differences were found in unipolar groups.	Negative