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Other Variant Report
Name | PIK3C3 -432C->T |
---|---|
Type | point mutation |
Related Gene | PIK3C3 |
No. of Study | 1 (Positive: 1; Negative 0; Trend: 0) |
Overlap with SZ? | YES |
Overlap with MDD? | NO |
Reference | Statistical Result | Description | Result Category |
---|---|---|---|
Stopkova, P., 2004 (a) | Allele frequency SZ vs. CONT, O2=1.31, P-value = 0.25 in American, Allele frequency SZ vs. CONT in Ashkenazi Jews, Fisher statistic=5.67, P-value = 0.02, Allele frequency SZ vs. CONT in Sephardic Jews, Fisher statistic=5.65, P-value = 0.02. Combined Ashkenazi and Sephardic sample SZ vs. CONT, Fisher statistic=12.81, P-value = 0.0003. | In the U.S. sample, there was no significant difference in the allele distribution between control subjects and patients with SZ and BD. A statistically significant difference in allele distribution was also detected in a cohort of patients with SZ from Israel. | Positive |