BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	MCP-1 A-2518G
Type	point mutation
Related Gene	CCL2
No. of Study	1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Roh, M. S., 2007	A/G		allelic P-value = 0.077, genotypic P-value = 0.209 for BD; allelic P-value = 0.144, genotypic P-value = 0.136 for male BD; allelic P-value = 0.299, genotypic P-value = 0.377 for female BD; allelic P-value = 0.077, genotypic P-value = 0.202 for BD1; allelic P-value = 0.157, genotypic P-value = 0.171 for male BD1; allelic P-value = 0.282, genotypic P-value = 0.189 for female BD1; allelic P-value = 0.517, genotypic P-value = 0.564 for BD2; allelic P-value = 0.555, genotypic P-value = 0.869 for male BD2; allelic P-value = 0.748, genotypic P-value = 0.827 for female BD2 in this sample; chi-square test, allelic P-value = 0.175, genotypic P-value = 0.163 for BD1 in the pooled data	No evidence of an association between the A-2518G polymorphi..... More No evidence of an association between the A-2518G polymorphism and BD, BD subtypes or BD in each gender was detected in either the allele frequency or genotype distribution in this sample. The allele and genotype frequencies were not significantly different between the pooled controls and pooled BD1 cases. Less	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)