BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Basic Info

Name	KCNN3 exon 1 CAG-repeat
Type	microsatellite
Location	exon 1
Related Gene	KCNN3
No. of Study	4 (Positive: 0; Negative 4; Trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Variant related studies (count: 4)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Glatt, S. J.,2003	CAG-repeat		Meta analysis:case-control study, chi square(4)=6.96, P-value = 0.14, and the pooled OR of 1.0 (95%CI=0.9-1.0)z= 0.04, P-value = 0.68;family based study, a pooled ORof 1.0 (95% CI=1.0-1.1), z=1.38, P-value = 0.17"	No significant association was observed in BD.	Negative
Ujike, H.,2001	short/long		Association analysis:chi sauqre test, chi square=0.55, d.f.=2, P-value = 0.76	No significant association was observed in BD.	Negative
Saleem, Q.,2000	short/long		Association analysis:chi sauqre test, chi square=3.88, df=8, P-value = 0.87	No significant association was observed in BD.	Negative
Jin, D. K.,2001	multi-allelic repeats		Association analysis:Fisher's Exact Test, P-value > 0.1	No significant association was observed in BD.	Negative

Overlap with SZ from cross-disorder studies (count: 3)

Reference	Statistical Result	Description	Result Category
Ujike, H.,2001	Association analysis:chi sauqre test, chi square=0.0, d.f.=2, P-value = 0.99	No significant association was observed in SZ.	Negative
Saleem, Q.,2000	Association analysis:chi sauqre test, chi square=8.35, df=8, P-value = 0.40	No significant association was observed in SZ.	Negative
Glatt, S. J.,2003	Meta analysis:case-control study, w(10)2 =15.20, P-value = 0.13, and the pooled OR of 1.0 pooled OR from 1, 596 cases and 1, 564 controls was 1.0(95% CI=1.0-1.1), z=1.15, P-value = 0.25;family based study, a pooled OR, z= 0.52, P-value = 0.61	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)