BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	DRD4 2-10 allele
Type	others
Related Gene	DRD4
No. of Study	1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Oruc, L., 1997 (a)			2 (218) Allele (bp): Fisherâ€™s exact test, P-value=1 for BPI, P-value=0.34 for BPI + UPR; 3 (266) Allele (bp): Fisherâ€™s exact test, P-value=1 for BPI, P-value=0.56 for BPI + UPR; 4 (314) Allele (bp): Fisherâ€™s exact test, P-value=1 for BPI, P-value=0.39 for BPI + UPR; 5 (362) Allele (bp): Fisherâ€™s exact test, P-value=1 for BPI, P-value=0.66 for BPI + UPR; 6 (410) Allele (bp): Fisherâ€™s exact test, P-value=0.74 for BPI, P-value=1 for BPI + UPR; 7 (458) Allele (bp): Fisherâ€™s exact test, P-value=0.55 for BPI, P-value=1 for BPI + UPR; 8 (506) Allele (bp): Fisherâ€™s exact test, P-value=0.28 for BPI, P-value=0.8 for BPI + UPR; 9 (554) Allele (bp): Fisherâ€™s exact test, P-value=0.48 for BPI, P-value=0.18 for BPI + UPR; 10 (602) Allele (bp): Fisherâ€™s exact test, P-value=0.74 for BPI, P-value=1 for BPI + UPR; Total: Fisherâ€™s exact test, P-value=0.38 for BPI, P-value=0.27 for BPI + UPR; Homozygotes: Fisherâ€™s exact test, P-value=1 for BPI, P-value=0.51 for BPI + UPR	No significant differences were observed at the single-allel..... More No significant differences were observed at the single-allele level when comparing the UPR, BPI, or combined patient populations vs. controls. Less	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Oruc, L., 1997 (a)	2 (218) Allele (bp): Fisherâ€™s exact test, P-value=0.18 for UPR, P-value=0.34 for BPI + UPR; 3 (266) Allele (bp): Fisherâ€™s exact test, P-value=0.49 for UPR, P-value=0.56 for BPI + UPR; 4 (314) Allele (bp): Fisherâ€™s exact test, P-value=0.19 for UPR, P-value=0.39 for BPI + UPR; 5 (362) Allele (bp): Fisherâ€™s exact test, P-value=1 for UPR, P-value=0.66 for BPI + UPR; 6 (410) Allele (bp): Fisherâ€™s exact test, P-value=1 for UPR, P-value=1 for BPI + UPR; 7 (458) Allele (bp): Fisherâ€™s exact test, P-value=0.71 for UPR, P-value=1 for BPI + UPR; 8 (506) Allele (bp): Fisherâ€™s exact test, P-value=0.8 for UPR, P-value=0.8 for BPI + UPR; 9 (554) Allele (bp): Fisherâ€™s exact test, P-value=0.44 for UPR, P-value=0.18 for BPI + UPR; 10 (602) Allele (bp): Fisherâ€™s exact test, P-value=1 for UPR, P-value=1 for BPI + UPR; Total: Fisherâ€™s exact test, P-value=0.26 for UPR, P-value=0.27 for BPI + UPR; Homozygotes: Fisherâ€™s exact test, P-value=0.24 for UPR, P-value=0.51 for BPI + UPR	No significant differences were observed at the single-allele level when comparing the UPR, BPI, or combined patient populations vs. controls.	Negative