BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Other Variant Report

Basic Info

Name	DRD2 -141CIns/Del
Type	insertion/deletion
Related Gene	DRD2
No. of Study	1 (Positive: 0; Negative 1; Trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Variant related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Furlong, R. A., 1998 (b)			allelic P-value=0.42, X²=0.65, df=1; genotypic P-value=0.09, X²=2.94, df=1; OR (95% CI)=0.83 (0.52-1.31) of allele 2 vs. 1, OR (95% CI)=0.64 (0.38-1.07) of 2 2 vs. 1 2 in bipolar; allelic P-value=0.72, X²=0.13, df=1; genotypic P-value=0.31, X²=1.03, df=1; OR (95% CI)=0.93 (0.63-1.38) of allele 2 vs. 1, OR (95% CI)=0.80 (0.51-1.24) of 2 2 vs. 1 2 in the combined sample	No significant association with this polymorphism was found ..... More No significant association with this polymorphism was found in either disorder, not even when both groups were combined to give an 'affective disorder' group. Less	Negative

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Furlong, R. A., 1998 (b)	allelic P-value=0.82, X²=0.06, df=1; genotypic P-value=0.91, X²=0.01, df=1; OR (95% CI)=1.06 (0.64-1.75) of allele 2 vs. 1, OR (95% CI)=1.03 (0.58-1.83) of 2 2 vs. 1 2 in bipolar; allelic P-value=0.72, X²=0.13, df=1; genotypic P-value=0.31, X²=1.03, df=1; OR (95% CI)=0.93 (0.63-1.38) of allele 2 vs. 1, OR (95% CI)=0.80 (0.51-1.24) of 2 2 vs. 1 2 in the combined sample	No significant association with this polymorphism was found in either disorder, not even when both groups were combined to give an 'affective disorder' group.	Negative