SNP Report

Basic Info

Name	rs900144 dbSNP Ensembl
Location	chr11:13272721 - 13272721(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.327077
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000527998, ENST00000529050, ENST00000534544)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value > 0.05, genotype P-value...... X²-tests: allele P-value > 0.05, genotype P-value > 0.05 in all model More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)

SNPs in LD with rs900144 (count: 16) View in gBrowse (chr11:13246839..13272721 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs1351522			0.915[CEU]
rs7942486			1.0[CEU]; 0.977[TSI]
rs1481879			0.916[CEU]
rs1481877			0.916[CEU]
rs1351520			0.836[CEU]
rs6486110			0.916[CEU]; 0.884[TSI]
rs4757133			0.954[CEU]
rs1481881			0.916[CEU]; 0.864[TSI]
rs11825506			0.911[CEU]
rs11022721			0.9[CEU]
rs4756763			0.916[CEU]; 0.842[TSI]
rs4757136			0.916[CEU]
rs11825504			0.915[CEU]; 0.841[TSI]
rs11603808			0.916[CEU]
rs4372426			0.916[CEU]
rs34369393			1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value = 0.181, Model Dominant, genotype P-value = 0.023, OR(95%CI)=0.69 (0.50-0.95)	Significant association was found.	Positive