SNP Report

Basic Info

Name	rs890319 dbSNP Ensembl
Location	chr15:26668487 - 26668487(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.275359
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000299267, ENST00000311550, ENST00000541819, ENST00000545868, ENST00000554556, ENST00000555094, ENST00000555632, ENST00000622697, ENST00000628124, ENST00000636466, ENST00000638099); NMD_transcript_variant(ENST00000554556, ENST00000555632); non_coding_transcript_variant(ENST00000555094); upstream_gene_variant(ENST00000635832)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Craddock, N., 2010			Nominal P-value = 0.00046 Nominal P-value = 0.00046	showed significant levels independent of the association at ...... showed significant levels independent of the association at the index SNP, rs7680321. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	15q12	3(1/2/0)

SNPs in LD with rs890319 (count: 1) View in gBrowse (chr15:26668487..26672011 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs1367959		intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.84[CEU]; 0.854[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)