SNP Report

Basic Info
Name rs885861 dbSNP Ensembl
Location chr7:159028856 - 159028856(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.310104
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000262178); downstream_gene_variant(ENST00000377633, ENST00000402066, ENST00000438049); non_coding_transcript_exon_variant(ENST00000413238); non_coding_transcript_variant(ENST00000413238)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Soria, V.,2010 X2-tests: allele P-value = 0.262, Model Recessive...... X2-tests: allele P-value = 0.262, Model Recessive, genotype P-value = 0.034, OR(95%CI)=1.61 (1.04-2.49) More... Significant association was found in BD. Significant association was found in BD. Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
VIPR2 vasoactive intestinal peptide receptor 2 7q36.3 1(1/0/0)
LINC00689 long intergenic non-protein coding RNA 689 7q36.3 Mapped by Literature SNP

SNPs in LD with rs885861 (count: 6) View in gBrowse (chr7:159005803..159028856 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Soria, V.,2010 X2-tests:allele P-value = 0.009, Model Recessive, genotype P-value = 0.004, OR(95%CI)=1.71 (1.18-2.46) Significant association was found. Positive