SNP Report

Basic Info

Name	rs885861 dbSNP Ensembl
Location	chr7:159028856 - 159028856(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.310104
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000262178); downstream_gene_variant(ENST00000377633, ENST00000402066, ENST00000438049); non_coding_transcript_exon_variant(ENST00000413238); non_coding_transcript_variant(ENST00000413238)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value = 0.262, Model Recessive...... X²-tests: allele P-value = 0.262, Model Recessive, genotype P-value = 0.034, OR(95%CI)=1.61 (1.04-2.49) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
VIPR2	vasoactive intestinal peptide receptor 2	7q36.3	1(1/0/0)
LINC00689	long intergenic non-protein coding RNA 689	7q36.3	Mapped by Literature SNP

SNPs in LD with rs885861 (count: 6) View in gBrowse (chr7:159005803..159028856 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs885863	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.92[CEU]; 0.977[TSI]
rs2527181	non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.92[CEU]
rs2730206	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.921[CEU]
rs2040897	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.847[CEU]; 0.893[TSI]
rs2527237	upstream_gene_variant	0.815[TSI]
rs1062610	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.96[CEU]; 0.978[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value = 0.009, Model Recessive, genotype P-value = 0.004, OR(95%CI)=1.71 (1.18-2.46)	Significant association was found.	Positive