SNP Report

Basic Info
Name rs7789727 dbSNP Ensembl
Location chrCHR_HSCHR7_1_CTG4_4:103182239 - 103182239(-1)
Variant Alleles G/A
Ancestral Allele A
Minor Allele A
Minor Allele Frequence 0.170128
Functional Annotation 5_prime_UTR_variant; downstream_gene_variant; intron_variant; upstream_gene_variant; non_coding_transcript_variant.
Consequence to Transcript 5_prime_UTR_variant(ENST00000341533, ENST00000417955, ENST00000418294, ENST00000425379, ENST00000465647); downstream_gene_variant(ENST00000426806); intron_variant(ENST00000427257); upstream_gene_variant(ENST00000422589, ENST00000479761, ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207); non_coding_transcript_variant(ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Pisanu, C., 2013 A/G logistic regression, P-value=0.581, OR=1.21 logistic regression, P-value=0.581, OR=1.21 Logistic regression analysis showed nominal association betw...... Logistic regression analysis showed nominal association between rs6465903 located in NAPE-PLD and BD, but not with lithium response. Separating the samples into two groups of BDI and BDII showed that these two SNPs were nominally associated with BDI but not with BDII. However, odds ratio (OR) was not significantly increased in comparison to the whole sample (SNP rs6465903,OR=1.42 in the whole sample and 1.44 in the BDI sample). More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 7q22.1 1(1/0/0)

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)