SNP Report

Basic Info

Name	rs7789727 dbSNP Ensembl
Location	chrCHR_HSCHR7_1_CTG4_4:103182239 - 103182239(-1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.170128
Functional Annotation	5_prime_UTR_variant; downstream_gene_variant; intron_variant; upstream_gene_variant; non_coding_transcript_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000341533, ENST00000417955, ENST00000418294, ENST00000425379, ENST00000465647); downstream_gene_variant(ENST00000426806); intron_variant(ENST00000427257); upstream_gene_variant(ENST00000422589, ENST00000479761, ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207); non_coding_transcript_variant(ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pisanu, C., 2013	A/G		logistic regression, P-value=0.581, OR=1.21 logistic regression, P-value=0.581, OR=1.21	Logistic regression analysis showed nominal association betw...... Logistic regression analysis showed nominal association between rs6465903 located in NAPE-PLD and BD, but not with lithium response. Separating the samples into two groups of BDI and BDII showed that these two SNPs were nominally associated with BDI but not with BDII. However, odds ratio (OR) was not significantly increased in comparison to the whole sample (SNP rs6465903,OR=1.42 in the whole sample and 1.44 in the BDI sample). More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D	7q22.1	1(1/0/0)

SNPs in LD with rs7789727 (count: 1) View in gBrowse (chrCHR_HSCHR7_1_CTG4_4:103182239..103300135 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs17156420		intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)