SNP Report

Basic Info

Name	rs7728378 dbSNP Ensembl
Location	chr5:76963525 - 76963525(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.453674
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000506501, ENST00000512446); intron_variant(ENST00000274368, ENST00000503763, ENST00000514258); non_coding_transcript_variant(ENST00000503763, ENST00000514258)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	C/T		Single SNP analyses: Permuted P-value = 0.151, Odds Ratio=1....... Single SNP analyses: Permuted P-value = 0.151, Odds Ratio=1.189 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRHBP	corticotropin releasing hormone binding protein	5q13.3	1(0/1/0)

SNPs in LD with rs7728378 (count: 2) View in gBrowse (chr5:76963525..76969210 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10055255		intron_variant; non_coding_transcript_variant	0.922[CEU]
rs1053989		3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.922[CEU]; 0.976[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)