SNP Report

Basic Info

Name	rs7718461 dbSNP Ensembl
Location	chr5:76962223 - 76962223(1)
Variant Alleles	A/G
Minor Allele	A
Minor Allele Frequence	0.460463
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000506501, ENST00000512446); intron_variant(ENST00000274368, ENST00000514258); non_coding_transcript_variant(ENST00000514258); upstream_gene_variant(ENST00000503763)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	G/A		Single SNP analyses: Permuted P-value = 0.2048, Odds Ratio=1...... Single SNP analyses: Permuted P-value = 0.2048, Odds Ratio=1.165 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRHBP	corticotropin releasing hormone binding protein	5q13.3	1(0/1/0)

SNPs in LD with rs7718461 (count: 2) View in gBrowse (chr5:76962223..76969210 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10055255		intron_variant; non_coding_transcript_variant	0.924[CEU]
rs1053989		3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.919[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)