SNP Report

Basic Info

Name	rs7619173 dbSNP Ensembl
Location	chr3:181279171 - 181279171(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.492013
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000460739, ENST00000469278, ENST00000493116, ENST00000493521, ENST00000597347, ENST00000626948, ENST00000630482); non_coding_transcript_variant(ENST00000460739, ENST00000469278, ENST00000493116, ENST00000493521, ENST00000597347, ENST00000626948, ENST00000630482)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kuo, P. H., 2014			P-value=0.00002,Â OR=0.5, 95%CI=0.4-0.7 for the second stage...... P-value=0.00002,Â OR=0.5, 95%CI=0.4-0.7 for the second stage, combined P-value=2E-04 for the replication stage. More...	The marker is identified to be associated with bipolar disor...... The marker is identified to be associated with bipolar disorder in the fine-mapping stage with P-value less than 0.05. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SOX2-OT	SOX2 overlapping transcript	3q26.33	Mapped by Literature SNP

SNPs in LD with rs7619173 (count: 7) View in gBrowse (chr3:181086683..181318431 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2567665	intron_variant; non_coding_transcript_variant	0.876[CHB]; 0.946[CHD]; 0.857[JPT]
rs9817763	intron_variant; non_coding_transcript_variant	0.8[CHB]; 0.824[CHD]
rs3860517	intron_variant; non_coding_transcript_variant	0.811[CHD]
rs9858313	intron_variant; non_coding_transcript_variant	0.813[CHD]
rs3109470	intron_variant; non_coding_transcript_variant	0.866[CHB]; 0.856[JPT]
rs3109469	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.876[CHB]; 0.947[CHD]; 0.857[JPT]
rs2718788	intron_variant; non_coding_transcript_variant	0.92[CHD]; 0.857[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)