SNP Report

Basic Info

Name	rs6901299 dbSNP Ensembl
Location	chr6:123454181 - 123454181(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.15016
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000334268, ENST00000418467, ENST00000427828, ENST00000434768, ENST00000587049, ENST00000587106, ENST00000589182, ENST00000625262, ENST00000625415, ENST00000628939, ENST00000629087); non_coding_transcript_variant(ENST00000418467, ENST00000427828, ENST00000434768, ENST00000587049, ENST00000587106, ENST00000589182, ENST00000625262, ENST00000625415, ENST00000628939, ENST00000629087)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Scott, L. J.,2009	G/A		NIMH/Pritzker: OR (95% CI)=1.05(0.86-1.27), P-value = 0.66; ...... NIMH/Pritzker: OR (95% CI)=1.05(0.86-1.27), P-value = 0.66; GSK(reduced sample): OR (95% CI)=1.18(0.95-1.46), P-value = 0.12; WTCCC: OR (95% CI)=1.26(1.15-1.39), P-value = 0.000002; 3-study meta-analysis: OR (95% CI)=1.21(1.11-1.31), P-value = 0.0000097; Heterogeneity: I²%=35, P-value = 0.21 More...		Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TRDN	triadin	6q22.31	Mapped by Literature SNP

SNPs in LD with rs6901299 (count: 12) View in gBrowse (chr6:123454181..123484284 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs7771575	intron_variant; non_coding_transcript_variant	0.938[CEU]
rs10499124	intron_variant; non_coding_transcript_variant	0.935[CEU]
rs4406254	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.935[CEU]
rs9490772	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.935[CEU]
rs7744051	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.937[CEU]
rs10499123	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.938[CEU]
rs13205992	intron_variant; non_coding_transcript_variant	0.938[CEU]
rs17739286	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.859[CEU]
rs1343640	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.938[CEU]
rs4434492	intron_variant; non_coding_transcript_variant	0.935[CEU]
rs9482391	intron_variant; non_coding_transcript_variant	0.938[CEU]
rs7751903	intron_variant; non_coding_transcript_variant	0.876[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)