BDgene

SNP Report

Basic Info
Name rs6481941 dbSNP Ensembl
Location chr10:35151213 - 35151213(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.373602
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000482646); intron_variant(ENST00000337656, ENST00000345491, ENST00000348787, ENST00000354759, ENST00000374721, ENST00000374726, ENST00000374728, ENST00000374734, ENST00000427847, ENST00000429130, ENST00000439705, ENST00000460270, ENST00000461968, ENST00000464475, ENST00000466251, ENST00000469949, ENST00000474362, ENST00000479070, ENST00000482633, ENST00000487132, ENST00000489321, ENST00000489388, ENST00000490460, ENST00000495960, ENST00000496019, ENST00000496626); NMD_transcript_variant(ENST00000464475, ENST00000490460, ENST00000495960); non_coding_transcript_variant(ENST00000461968, ENST00000466251, ENST00000482633, ENST00000489388, ENST00000496019, ENST00000496626)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Crisafulli, C.,2012 A/G Association analysis: genotype P-value = 0.24, chi square=7....... Association analysis: genotype P-value = 0.24, chi square=7.95; allele P-value = 0.09, chi square=4.84 More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CREM cAMP responsive element modulator 10p12.1-p11.1 1(0/1/0)

SNPs in LD with rs6481941 (count: 112) View in gBrowse (chr10:34968895..35265126 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 112)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Crisafulli, C.,2012 Association analysis:genotype P-value = >0.05;allele P-value > 0.05 No significant association was observed in MDD. Negative

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
To view this website normally, please make sure to allow Flash to run from the local filesystem in the security settings panel.
Last update: March 31, 2016