SNP Report

Basic Info

Name	rs5761499 dbSNP Ensembl
Location	chr22:26371052 - 26371052(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.435703
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000248933, ENST00000343706, ENST00000360929, ENST00000402979, ENST00000403121, ENST00000404234, ENST00000494013, ENST00000529632, ENST00000629590); non_coding_transcript_variant(ENST00000494013)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, C.,2012		G	Gene-gender interaction:OR = 0.88,P-value = 0.0011;Male:OR =...... Gene-gender interaction:OR = 0.88,P-value = 0.0011;Male:OR = 0.87,P-value = 0.17;Female:OR = 0.7,P-value = 0.004,P-value corrected = 0.064 More...	16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD...... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD-I(P<0.01). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SEZ6L	seizure related 6 homolog (mouse)-like	22q12.1	1(1/0/0)

SNPs in LD with rs5761499 (count: 3) View in gBrowse (chr22:26371052..26381474 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs738400	intron_variant; non_coding_transcript_variant	0.801[TSI]
rs5761503	3_prime_UTR_variant; downstream_gene_variant	0.847[TSI]
rs5752315	3_prime_UTR_variant; downstream_gene_variant	0.847[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)