SNP Report

Basic Info

Name	rs4822693 dbSNP Ensembl
Location	chr22:26237212 - 26237212(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.21226
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000414989); intron_variant(ENST00000248933, ENST00000343706, ENST00000360929, ENST00000404234, ENST00000529632, ENST00000629590)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, C.,2012		T	Gene-gender interaction:OR = 0.81,P-value = 0.00016;Male:OR ...... Gene-gender interaction:OR = 0.81,P-value = 0.00016;Male:OR = 0.89,P-value = 0.36;Female:OR = 0.74,P-value = 0.0003,P-value corrected = 0.0048 More...	16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD...... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD-I(P<0.01). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SEZ6L	seizure related 6 homolog (mouse)-like	22q12.1	1(1/0/0)

SNPs in LD with rs4822693 (count: 9) View in gBrowse (chr22:26224278..26243002 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1535145	intron_variant	1.0[CEU]; 1.0[TSI]
rs2207607	intron_variant	1.0[CEU]
rs5761423	intron_variant	1.0[CEU]
rs2207606	intron_variant	1.0[CEU]
rs4239917	intron_variant; non_coding_transcript_variant	0.851[CEU]
rs11703532	intron_variant	1.0[CEU]
rs4438594	intron_variant; non_coding_transcript_variant	0.851[CEU]
rs4140478	intron_variant	1.0[CEU]
rs5761434	intron_variant; non_coding_transcript_variant	0.851[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)