BDgene

SNP Report

Basic Info
Name rs4822693 dbSNP Ensembl
Location chr22:26237212 - 26237212(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.21226
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000414989); intron_variant(ENST00000248933, ENST00000343706, ENST00000360929, ENST00000404234, ENST00000529632, ENST00000629590)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Xu, C.,2012 T Gene-gender interaction:OR = 0.81,P-value = 0.00016;Male:OR ...... Gene-gender interaction:OR = 0.81,P-value = 0.00016;Male:OR = 0.89,P-value = 0.36;Female:OR = 0.74,P-value = 0.0003,P-value corrected = 0.0048 More... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD...... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD-I(P<0.01). More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SEZ6L seizure related 6 homolog (mouse)-like 22q12.1 1(1/0/0)

SNPs in LD with rs4822693 (count: 9) View in gBrowse (chr22:26224278..26243002 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 9)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)