SNP Report

Basic Info

Name	rs4131347 dbSNP Ensembl
Location	chr12:71930591 - 71930591(1)
Variant Alleles	G/A/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.396166
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000550746)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mann, J. J., 2008	G/C		Genotypic P-value = 0.388, allelic P-value = 0.863 for BD wh...... Genotypic P-value = 0.388, allelic P-value = 0.863 for BD when compared with controls. More...	There were no differences between BD and healthy volunteers ...... There were no differences between BD and healthy volunteers in genotype or allelic frequency. More...	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TBC1D15	TBC1 domain family, member 15	12q15	Mapped by Literature SNP
TPH2	tryptophan hydroxylase 2	12q15	13(10/3/0)

SNPs in LD with rs4131347 (count: 0) View in gBrowse (chr12:71930591..71930591 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mann, J. J., 2008	Genotypic P-value = 0.684, allelic P-value = 0.502 for MDD when compared with controls.	There were no differences between MDD and healthy volunteers in genotype or allelic frequency.	Negative