SNP Report

Basic Info

Name	rs3794730 dbSNP Ensembl
Location	chr17:29823341 - 29823341(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.185304
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000269033, ENST00000394848, ENST00000540801, ENST00000577483, ENST00000578411, ENST00000579040, ENST00000592397); NMD_transcript_variant(ENST00000579040); non_coding_transcript_variant(ENST00000394848, ENST00000577483, ENST00000578411)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Alaerts, M.,2009	A/G		Allelic association P-value = 0.80; Genotypic association P-...... Allelic association P-value = 0.80; Genotypic association P-value = 0.80 More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4	17q11.2	44(18/26/0)
SSH2	slingshot protein phosphatase 2	17q11.2	Mapped by Literature SNP

SNPs in LD with rs3794730 (count: 2) View in gBrowse (chr17:29632885..30000564 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs2289629		intron_variant; missense_variant; non_coding_transcript_variant; upstream_gene_variant	0.867[CEU]
rs11868086		downstream_gene_variant; intron_variant; NMD_transcript_variant	0.913[CEU]; 0.881[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)