SNP Report

Basic Info

Name	rs3793227 dbSNP Ensembl
Location	chr7:159093237 - 159093237(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.124201
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000262178, ENST00000377633, ENST00000402066)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value = 0.047, Model Log-addit...... X²-tests: allele P-value = 0.047, Model Log-additive, genotype P-value = 0.039, OR(95%CI)=0.66 (0.45-0.99) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
VIPR2	vasoactive intestinal peptide receptor 2	7q36.3	1(1/0/0)

SNPs in LD with rs3793227 (count: 10) View in gBrowse (chr7:159070845..159139768 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs3793237	intron_variant	1.0[CEU]; 0.919[TSI]
rs17837880	intron_variant	1.0[CEU]
rs3793222	intron_variant	1.0[CEU]; 1.0[TSI]
rs2270314	intron_variant	1.0[CEU]
rs3812313	intron_variant	0.825[CEU]
rs17837875	intron_variant	0.941[CEU]; 0.919[TSI]
rs6459928	intron_variant	0.825[CEU]
rs3828962	intron_variant	1.0[CEU]
rs17837881	intron_variant	1.0[CEU]; 0.916[TSI]
rs3793223	intron_variant	1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative