SNP Report

Basic Info

Name	rs2978012 dbSNP Ensembl
Location	chr8:133526953 - 133526953(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.194289
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000399640, ENST00000517668, ENST00000518298, ENST00000519435, ENST00000521180, ENST00000522652, ENST00000522873); non_coding_transcript_variant(ENST00000518298, ENST00000519435, ENST00000522873)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Perlis, 2008			Mean X²=6.82, P-value = 0.009 in gene-based assoc...... Mean X²=6.82, P-value = 0.009 in gene-based association tests More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	8q24.22	4(3/0/1)

SNPs in LD with rs2978012 (count: 3) View in gBrowse (chr8:133526953..133529299 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2978015	intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.954[TSI]
rs2945779	intron_variant; non_coding_transcript_variant	0.919[CEU]; 0.977[TSI]
rs2978014	intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)