SNP Report

Basic Info

Name	rs2837500 dbSNP Ensembl
Location	chr21:40205968 - 40205968(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.478235
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000400454, ENST00000404019, ENST00000617870)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Amano, K., 2008	T/C		Genotypic P-value = 0.5896, allelic P-value = 0.7894 for BD ...... Genotypic P-value = 0.5896, allelic P-value = 0.7894 for BD when compared with controls More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DSCAM	Down syndrome cell adhesion molecule	21q22.2-q22.3	3(1/2/0)

SNPs in LD with rs2837500 (count: 46) View in gBrowse (chr21:40191313..40243234 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 46)

rs_ID	Functional Annotation	r²[population]
rs8131481	downstream_gene_variant; intron_variant	0.867[CHB]; 0.868[CHD]; 0.906[JPT]
rs2837521	intron_variant	0.822[JPT]
rs2837510	intron_variant; upstream_gene_variant	0.826[CHB]; 0.822[JPT]
rs7283077	intron_variant; upstream_gene_variant	0.826[CHB]; 0.863[JPT]
rs2837501	intron_variant	0.889[CEU]; 0.913[TSI]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs9982745	intron_variant	0.826[CHB]; 0.863[JPT]
rs1997551	intron_variant; upstream_gene_variant	0.826[CHB]; 0.822[JPT]
rs1571721	intron_variant	1.0[CEU]; 0.977[TSI]; 1.0[CHB]; 0.977[CHD]; 1.0[JPT]
rs2837494	intron_variant	0.889[CEU]; 1.0[CHB]; 1.0[JPT]
rs8130627	intron_variant	0.822[JPT]
rs13049234	intron_variant	0.867[CHB]; 0.889[CHD]; 0.904[JPT]
rs2837508	intron_variant; upstream_gene_variant	0.826[CHB]; 0.822[JPT]
rs760170	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2837507	downstream_gene_variant; intron_variant	0.826[CHB]; 0.863[JPT]
rs2837503	intron_variant	0.864[CHB]; 0.906[JPT]
rs7281120	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs8127634	intron_variant	0.821[TSI]
rs9984703	intron_variant	0.889[CEU]; 0.913[TSI]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2837518	intron_variant	0.826[CHB]; 0.863[JPT]
rs2014678	intron_variant	0.847[CEU]; 0.907[CHB]; 0.906[JPT]
rs2837517	intron_variant	0.826[CHB]; 0.863[JPT]
rs1571718	intron_variant	1.0[CEU]; 0.977[TSI]; 1.0[CHB]; 0.977[CHD]; 1.0[JPT]
rs9984694	intron_variant	1.0[CEU]; 0.977[TSI]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs11702340	intron_variant	0.923[CEU]; 0.909[CHB]
rs2837490	intron_variant	0.821[TSI]
rs13052377	intron_variant; upstream_gene_variant	0.826[CHB]; 0.822[JPT]
rs8128592	intron_variant	0.818[CEU]
rs2837516	intron_variant	0.826[CHB]; 0.863[JPT]
rs2205141	intron_variant	0.823[TSI]
rs2837492	intron_variant	0.867[TSI]
rs960697	intron_variant	0.822[JPT]
rs2837502	intron_variant	0.954[CHB]; 0.932[CHD]; 0.951[JPT]
rs2837512	intron_variant	0.822[JPT]
rs4818120	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2837515	intron_variant	0.826[CHB]; 0.863[JPT]
rs1554937	intron_variant	0.867[CHB]; 0.909[CHD]; 0.906[JPT]
rs2837499	intron_variant	1.0[CEU]; 1.0[TSI]; 0.822[JPT]
rs4375957	intron_variant	0.867[CHB]; 0.906[JPT]
rs7278621	intron_variant	0.821[TSI]
rs10222133	intron_variant	0.923[CEU]; 0.909[CHB]
rs726104	intron_variant	0.961[CEU]; 1.0[CHB]; 0.953[CHD]
rs2837529	intron_variant	0.876[CHB]
rs1554922	intron_variant	0.822[JPT]
rs2837497	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs1571719	intron_variant	0.887[CEU]; 1.0[CHB]; 1.0[JPT]
rs2837485	intron_variant	0.821[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)