SNP Report

Basic Info

Name	rs2837399 dbSNP Ensembl
Location	chr21:40055397 - 40055397(1)
Variant Alleles	G/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.496605
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000400454, ENST00000404019, ENST00000617870)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Amano, K., 2008	A/C		Genotypic P-value = 0.8482, allelic P-value = 0.9288 for BD ...... Genotypic P-value = 0.8482, allelic P-value = 0.9288 for BD when compared with controls More...	Strong LD existed in the genomic stretch between DC118 and D...... Strong LD existed in the genomic stretch between DC118 and DC147 SNPs More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DSCAM	Down syndrome cell adhesion molecule	21q22.2-q22.3	3(1/2/0)

SNPs in LD with rs2837399 (count: 17) View in gBrowse (chr21:40044911..40064718 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs8133326	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2837395	intron_variant	1.0[CEU]; 1.0[TSI]; 1.0[CHB]; 0.952[CHD]; 1.0[JPT]
rs10470192	intron_variant	0.897[CHB]; 0.813[JPT]
rs2837396	intron_variant	0.869[CHB]; 0.867[JPT]
rs2837403	intron_variant	0.958[CEU]; 0.976[TSI]; 1.0[CHB]; 0.868[CHD]; 1.0[JPT]
rs2837393	intron_variant	1.0[CEU]; 1.0[TSI]; 1.0[CHB]; 0.953[CHD]; 1.0[JPT]
rs4239808	intron_variant	0.958[CEU]; 0.902[CHB]; 1.0[JPT]
rs2410204	intron_variant	0.876[CEU]; 0.862[CHB]; 1.0[JPT]
rs2222999	intron_variant	0.917[CEU]; 1.0[TSI]; 0.953[CHB]; 0.909[CHD]; 0.951[JPT]
rs2837385	intron_variant	0.958[CEU]; 0.859[CHB]; 1.0[JPT]
rs2837381	intron_variant	0.956[CEU]; 0.906[TSI]; 0.862[CHB]; 0.929[CHD]; 1.0[JPT]
rs2837404	intron_variant	1.0[CHB]; 1.0[JPT]
rs4816672	intron_variant	0.897[CEU]; 0.949[CHB]; 1.0[JPT]
rs2837401	intron_variant	1.0[CHB]; 1.0[JPT]
rs2837398	intron_variant	0.958[CEU]; 0.976[TSI]; 1.0[CHB]; 0.868[CHD]; 1.0[JPT]
rs2837411	intron_variant	0.868[CHB]; 0.826[JPT]
rs2410205	intron_variant	0.959[CEU]; 0.906[TSI]; 0.862[CHB]; 0.906[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)