SNP Report

Basic Info

Name	rs2373721 dbSNP Ensembl
Location	chr12:102433267 - 102433267(1)
Variant Alleles	G/C
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.221246
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000307046, ENST00000337514, ENST00000392904, ENST00000392905, ENST00000424202, ENST00000456098, ENST00000635615); non_coding_transcript_variant(ENST00000635615)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pereira, A. C.,2011	G/C		X² tests: X²=1.308, P-value = 0.253 X² tests: X²=1.308, P-value = 0.253	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
IGF1	insulin-like growth factor 1 (somatomedin C)	12q23.2	1(1/0/0)

SNPs in LD with rs2373721 (count: 12) View in gBrowse (chr12:102405458..102459394 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10860865	intron_variant; non_coding_transcript_variant	0.944[CEU]
rs7296464	intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs4764697	intron_variant; non_coding_transcript_variant	0.807[TSI]
rs2288378	intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs10735380	intron_variant; non_coding_transcript_variant	0.847[CEU]; 1.0[TSI]
rs6539035	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs9989002	intron_variant; non_coding_transcript_variant	0.846[CEU]; 1.0[TSI]
rs5742694	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]
rs4764696	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs972936	intron_variant; non_coding_transcript_variant	0.945[CEU]; 1.0[TSI]
rs5009837	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.847[CEU]; 0.901[TSI]
rs5742667	intron_variant; non_coding_transcript_variant	0.945[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)