SNP Report

Basic Info

Name	rs2304673 dbSNP Ensembl
Location	chr2:238277281 - 238277281(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.0890575
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000254657, ENST00000355768, ENST00000431832); non_coding_transcript_variant(ENST00000355768)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value > 0.05, genotype P-value...... X²-tests: allele P-value > 0.05, genotype P-value > 0.05 in all model More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PER2	period circadian clock 2	2q37.3	7(1/6/0)

SNPs in LD with rs2304673 (count: 1) View in gBrowse (chr2:238277281..238294273 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs4617993		downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value = 0.076, Model Dominant, genotype P-value = 0.049, OR(95%CI)=1.39 (1.00-1.94)	Significant association was found.	Positive