SNP Report

Basic Info

Name	rs2279550 dbSNP Ensembl
Location	chr4:188091574 - 188091574(1)
Variant Alleles	G/A/C
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.28754
Functional Annotation	3_prime_UTR_variant; NMD_transcript_variant; synonymous_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000503141, ENST00000503475); NMD_transcript_variant(ENST00000503141, ENST00000503475); synonymous_variant(ENST00000326754, ENST00000512729)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Blair, I. P.,2005	G/C		X² goodness of fit tests: MAF=0.49, Genotype P-va...... X² goodness of fit tests: MAF=0.49, Genotype P-value = 0.9, Allele P-value = 0.7 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TRIML2	tripartite motif family-like 2	4q35.2	1(0/1/0)

SNPs in LD with rs2279550 (count: 2) View in gBrowse (chr4:188090020..188100311 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs902909		intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.953[CEU]
rs12647135		downstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)