BDgene

SNP Report

Basic Info
Name rs2242663 dbSNP Ensembl
Location chr11:66567837 - 66567837(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.208267
Functional Annotation downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000502692, ENST00000513398); intron_variant(ENST00000310325, ENST00000526010); upstream_gene_variant(ENST00000524994, ENST00000525733, ENST00000527141, ENST00000529199, ENST00000529561, ENST00000530565, ENST00000533168)
No. of Studies 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Scott, L. J.,2009 T/C NIMH/Pritzker: OR (95% CI)=1.29(1.09-1.53), P-value = 0.0028...... NIMH/Pritzker: OR (95% CI)=1.29(1.09-1.53), P-value = 0.0028; GSK(reduced sample): OR (95% CI)=1.32(1.10-1.59), P-value = 0.0024; WTCCC: OR (95% CI)=1.15(1.05-1.25), P-value = 0.0015; 3-study meta-analysis: OR (95% CI)=1.2(1.11-1.29), P-value = 0.0000013; Heterogeneity: I2%=33, P-value = 0.23 More... Trend

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ACTN3 actinin, alpha 3 (gene/pseudogene) 11q13.2 Mapped by Literature SNP
CTSF cathepsin F 11q13.2 Mapped by Literature SNP

SNPs in LD with rs2242663 (count: 0) View in gBrowse (chr11:66567837..66567837 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)