SNP Report

Basic Info

Name	rs2144719 dbSNP Ensembl
Location	chr1:66357451 - 66357451(1)
Variant Alleles	G/T
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.188698
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000329654, ENST00000341517, ENST00000371045, ENST00000423207, ENST00000480109, ENST00000526197, ENST00000528771, ENST00000531025, ENST00000534463); non_coding_transcript_variant(ENST00000534463); upstream_gene_variant(ENST00000524999)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kahler, A. K., 2010	T/G	T	genotype test: P-value = 0.044, allele test: P-value = and ...... genotype test: P-value = 0.044, allele test: P-value = and OR=1.02 for all samples, OR=1.03 in Denmark samples, OR=1.02 in Normay samples. More...	nominally significant in allele- or genotype-based tests, no...... nominally significant in allele- or genotype-based tests, none of the tagSNPs remained significantly associated with BP after correction for multiple testing. None of the tagSNPs nominally associated with BP were associated with positive or negative symptoms in the BP sample. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PDE4B	phosphodiesterase 4B, cAMP-specific	1p31	3(1/2/0)

SNPs in LD with rs2144719 (count: 0) View in gBrowse (chr1:66357451..66357451 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)