SNP Report

Basic Info

Name	rs1875999 dbSNP Ensembl
Location	chr5:76969157 - 76969157(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.427516
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000274368); downstream_gene_variant(ENST00000503763); intron_variant(ENST00000514258); non_coding_transcript_variant(ENST00000514258)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	G/A		Single SNP analyses: Permuted P-value = 0.07978, Odds Ratio=...... Single SNP analyses: Permuted P-value = 0.07978, Odds Ratio=1.243 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRHBP	corticotropin releasing hormone binding protein	5q13.3	1(0/1/0)

SNPs in LD with rs1875999 (count: 3) View in gBrowse (chr5:76968168..76969697 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10055255	intron_variant; non_coding_transcript_variant	0.812[CEU]
rs1053989	3_prime_UTR_variant; downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.812[CEU]
rs2174444	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)