SNP Report

Basic Info
Name rs17452383 dbSNP Ensembl
Location chr11:13388824 - 13388824(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.0828674
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; NMD_transcript_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000278174, ENST00000527102, ENST00000528120, ENST00000530907); downstream_gene_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403482, ENST00000403510, ENST00000472842, ENST00000524392); NMD_transcript_variant(ENST00000527102)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Soria, V.,2010 X2-tests: allele P-value > 0.05, genotype P-value...... X2-tests: allele P-value > 0.05, genotype P-value > 0.05 in all model More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ARNTL aryl hydrocarbon receptor nuclear translocator-like 11p15 7(5/2/0)
BTBD10 BTB (POZ) domain containing 10 11p15.2 Mapped by Literature SNP

SNPs in LD with rs17452383 (count: 2) View in gBrowse (chr11:13388824..13459549 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Soria, V.,2010 X2-tests:allele P-value = 0.938, Model Recessive, genotype P-value = 0.035, OR(95%CI)=3.00 (1.03-8.77) Significant association was found. Positive