SNP Report

Basic Info

Name	rs17305959 dbSNP Ensembl
Location	chr22:26339666 - 26339666(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.209265
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000248933, ENST00000343706, ENST00000360929, ENST00000402979, ENST00000403121, ENST00000404234, ENST00000529632, ENST00000629590)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, C.,2012		A	Gene-gender interaction:OR = 1.18,P-value = 0.00033;Male:OR ...... Gene-gender interaction:OR = 1.18,P-value = 0.00033;Male:OR = 1.21,P-value = 0.097;Female:OR = 1.47,P-value = 0.00028,P-value corrected = 0.0045 More...	16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD...... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD-I(P<0.01). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SEZ6L	seizure related 6 homolog (mouse)-like	22q12.1	1(1/0/0)

SNPs in LD with rs17305959 (count: 3) View in gBrowse (chr22:26335690..26340846 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs926371	intron_variant	0.954[CEU]
rs3788386	intron_variant	0.91[CEU]; 0.966[TSI]
rs5761481	intron_variant	0.91[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)