SNP Report

Basic Info

Name	rs17100289 dbSNP Ensembl
Location	chr5:143429077 - 143429077(1)
Variant Alleles	T/A
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.488219
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000343796, ENST00000503701, ENST00000504572, ENST00000505058); non_coding_transcript_variant(ENST00000503701, ENST00000505058)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	T/A		Single SNP analyses: Permuted P-value = 0.1402, Odds Ratio=0...... Single SNP analyses: Permuted P-value = 0.1402, Odds Ratio=0.8335 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	5q31-q32	5(2/3/0)

SNPs in LD with rs17100289 (count: 4) View in gBrowse (chr5:143426309..143429707 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs12054797	intron_variant; non_coding_transcript_variant	0.831[CEU]
rs4912910	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs12655166	intron_variant; non_coding_transcript_variant	0.831[CEU]
rs10477211	intron_variant; non_coding_transcript_variant	0.831[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)