SNP Report

Basic Info

Name	rs17083008 dbSNP Ensembl
Location	chr6:152746792 - 152746792(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.284744
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000367243, ENST00000367244)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value = 0.062, Model Recessive...... X²-tests: allele P-value = 0.062, Model Recessive, genotype P-value = 0.004, OR(95%CI)=2.68 (1.37-5.22) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
VIP	vasoactive intestinal peptide	6q24-q27	1(1/0/0)

SNPs in LD with rs17083008 (count: 1) View in gBrowse (chr6:152746792..152753187 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs3823082		intron_variant; upstream_gene_variant	0.943[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative