SNP Report

Basic Info

Name	rs16981987 dbSNP Ensembl
Location	chr22:26379688 - 26379688(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.0511182
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000494013); intron_variant(ENST00000248933, ENST00000343706, ENST00000360929, ENST00000402979, ENST00000403121, ENST00000404234, ENST00000529632, ENST00000629590)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, C.,2012		C	Gene-gender interaction:OR = 1.61,P-value = 0.0012;Male:OR =...... Gene-gender interaction:OR = 1.61,P-value = 0.0012;Male:OR = 1.56,P-value = 0.12;Female:OR = 2.58,P-value = 0.0031,P-value corrected = 0.049 More...	16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD...... 16 SNPsshowedsignificantgenexgenderinteractionsinfluencingBD-I(P<0.01). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SEZ6L	seizure related 6 homolog (mouse)-like	22q12.1	1(1/0/0)

SNPs in LD with rs16981987 (count: 2) View in gBrowse (chr22:26379543..26382319 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs5997085		3_prime_UTR_variant; downstream_gene_variant	1.0[CEU]
rs16981985		downstream_gene_variant; intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)