BDgene

SNP Report

Basic Info
Name rs16935888 dbSNP Ensembl
Location chr10:35143477 - 35143477(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.159744
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000337656, ENST00000345491, ENST00000354759, ENST00000374721, ENST00000374726, ENST00000374728, ENST00000374734, ENST00000427847, ENST00000429130, ENST00000439705, ENST00000460270, ENST00000461968, ENST00000466251, ENST00000469949, ENST00000474362, ENST00000479070, ENST00000482633, ENST00000482646, ENST00000487132, ENST00000489321, ENST00000489388, ENST00000490460, ENST00000495960, ENST00000496019, ENST00000496626); NMD_transcript_variant(ENST00000490460, ENST00000495960); non_coding_transcript_variant(ENST00000461968, ENST00000466251, ENST00000482633, ENST00000482646, ENST00000489388, ENST00000496019, ENST00000496626); upstream_gene_variant(ENST00000348787, ENST00000464475)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Crisafulli, C.,2012 C/T Association analysis: genotype P-value = 0.38, chi square=4....... Association analysis: genotype P-value = 0.38, chi square=4.19; allele P-value = 0.16, chi square=3.66 More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CREM cAMP responsive element modulator 10p12.1-p11.1 1(0/1/0)

SNPs in LD with rs16935888 (count: 27) View in gBrowse (chr10:34978439..35266019 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 27)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Crisafulli, C.,2012 Association analysis:genotype P-value = >0.05;allele P-value > 0.05 No significant association was observed in MDD. Negative

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016