SNP Report

Basic Info

Name	rs1644454 dbSNP Ensembl
Location	chr5:161317984 - 161317984(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.375
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000274547, ENST00000353437, ENST00000393959, ENST00000517547, ENST00000517901, ENST00000520240)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Perlis, 2008			Mean X²=5.97, P-value = 0.003 in gene-based assoc...... Mean X²=5.97, P-value = 0.003 in gene-based association tests More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	5q34	1(1/0/0)

SNPs in LD with rs1644454 (count: 7) View in gBrowse (chr5:161288871..161325990 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs252980	intron_variant	0.913[CEU]
rs252947	3_prime_UTR_variant; downstream_gene_variant	0.802[CEU]
rs253003	intron_variant	1.0[CEU]
rs1644517	downstream_gene_variant; intron_variant	1.0[CEU]
rs253002	intron_variant	1.0[CEU]
rs2546619	intron_variant	1.0[CEU]
rs1677381	downstream_gene_variant; intron_variant	0.859[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)