SNP Report

Basic Info

Name	rs1512343 dbSNP Ensembl
Location	chr4:148329805 - 148329805(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.212859
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000342437, ENST00000344721, ENST00000358102, ENST00000504753, ENST00000511528, ENST00000512865, ENST00000625323); NMD_transcript_variant(ENST00000342437); non_coding_transcript_variant(ENST00000504753)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ceulemans, S.,2011	T/C		Single SNP analyses: Permuted P-value = 0.17, Odds Ratio=0.8...... Single SNP analyses: Permuted P-value = 0.17, Odds Ratio=0.8379 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NR3C2	nuclear receptor subfamily 3, group C, member 2	4q31	1(1/0/0)

SNPs in LD with rs1512343 (count: 5) View in gBrowse (chr4:148329805..148348844 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10034789	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.832[CEU]
rs7700126	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.838[CEU]
rs17484601	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CEU]
rs4835136	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.845[CEU]
rs10519959	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.845[CEU]; 0.818[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)