SNP Report

Basic Info

Name	rs13259346 dbSNP Ensembl
Location	chr8:32653487 - 32653487(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.337859
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000287842, ENST00000356819, ENST00000405005, ENST00000518104, ENST00000518206, ENST00000519301, ENST00000520407, ENST00000520502, ENST00000521670, ENST00000522569, ENST00000523041, ENST00000523079, ENST00000523534, ENST00000631040); non_coding_transcript_variant(ENST00000522569)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cao L., 2014	G/A		Total BPI vs. controls: X²=1.5, OR=1.15, 95%CI=0....... Total BPI vs. controls: X²=1.5, OR=1.15, 95%CI=0.92-1.44, Bonf P-value=1; BPI-P vs. controls: X²=0.25, OR=1.07, 95%CI=0.83-1.38, Bonf P-value=1; BPI-NP vs. controls: X²=2.32, OR=1.31, 95%CI=0.92-1.86, Bonf P-value=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs13259346 (count: 1) View in gBrowse (chr8:32650520..32653487 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs13282195		intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)