BDgene

SNP Report

Basic Info
Name rs129974 dbSNP Ensembl
Location chr16:3745291 - 3745291(1)
Variant Alleles G/A/T
Ancestral Allele G
Minor Allele T
Minor Allele Frequence 0.0776757
Functional Annotation downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000638158); non_coding_transcript_exon_variant(ENST00000572569); non_coding_transcript_variant(ENST00000572569); synonymous_variant(ENST00000262367, ENST00000382070, ENST00000570939, ENST00000573517); upstream_gene_variant(ENST00000574740, ENST00000576720, ENST00000635919)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Crisafulli, C.,2012 G/T Association analysis: genotype P-value = 0.73, chi square=2....... Association analysis: genotype P-value = 0.73, chi square=2.03; allele P-value = 0.83, chi square=0.36 More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CREBBP CREB binding protein 16p13.3 1(0/1/0)

SNPs in LD with rs129974 (count: 25) View in gBrowse (chr16:3734355..3883344 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 25)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Crisafulli, C.,2012 Association analysis:genotype P-value = >0.05;allele P-value > 0.05 No significant association was observed in MDD. Negative