SNP Report

Basic Info

Name	rs11578058 dbSNP Ensembl
Location	chr1:173743991 - 173743991(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0515176
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000455497); intron_variant(ENST00000209884)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	T/C		P(unadj)-value=1.30E-04,Â OR (unadj)=0.6925,Â P(adj)-value=6...... P(unadj)-value=1.30E-04,Â OR (unadj)=0.6925,Â P(adj)-value=6.46E-05,Â OR (adj)=0.6715 More...	Top 68 SNPs (showing suggestive association to BD: p<0.0001)...... Top 68 SNPs (showing suggestive association to BD: p<0.0001) in our combined (CAMH and IoP) GWAS. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
KLHL20	kelch-like family member 20	1q25.1	1(0/1/0)

SNPs in LD with rs11578058 (count: 2) View in gBrowse (chr1:173600037..173743991 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10912656		intron_variant; upstream_gene_variant	0.913[TSI]
rs17350830		intron_variant; non_coding_transcript_variant	0.827[CEU]; 0.958[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)