SNP Report

Basic Info
Name rs1148247 dbSNP Ensembl
Location chr10:35208018 - 35208018(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.289337
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000466251, ENST00000494479); intron_variant(ENST00000337656, ENST00000342105, ENST00000344351, ENST00000345491, ENST00000348787, ENST00000354759, ENST00000356917, ENST00000361599, ENST00000374721, ENST00000374728, ENST00000374734, ENST00000395887, ENST00000429130, ENST00000439705, ENST00000460270, ENST00000461968, ENST00000463314, ENST00000463960, ENST00000464475, ENST00000468236, ENST00000469517, ENST00000473940, ENST00000474362, ENST00000474931, ENST00000479070, ENST00000484283, ENST00000487132, ENST00000487763, ENST00000488328, ENST00000488741, ENST00000490460, ENST00000490511, ENST00000495960); NMD_transcript_variant(ENST00000464475, ENST00000490460, ENST00000495960); non_coding_transcript_variant(ENST00000461968, ENST00000469517); upstream_gene_variant(ENST00000602435)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Crisafulli, C.,2012 A/G Association analysis: genotype P-value = 0.52, chi square=3....... Association analysis: genotype P-value = 0.52, chi square=3.23; allele P-value = 0.68, chi square=0.77 More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
CREM cAMP responsive element modulator 10p12.1-p11.1 1(0/1/0)

SNPs in LD with rs1148247 (count: 1) View in gBrowse (chr10:35034202..35208018 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Crisafulli, C.,2012 Association analysis:genotype P-value = >0.05;allele P-value > 0.05 No significant association was observed in MDD. Negative