SNP Report

Basic Info

Name	rs1106855 dbSNP Ensembl
Location	chr2:75050860 - 75050860(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.238019
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000409848); intron_variant(ENST00000305249)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Perlis, 2008			Mean X²=5.14, P-value = 0.004 in gene-based assoc...... Mean X²=5.14, P-value = 0.004 in gene-based association tests More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TACR1	tachykinin receptor 1	2p13.1-p12	3(3/0/0)

SNPs in LD with rs1106855 (count: 20) View in gBrowse (chr2:74939766..75050860 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11126449		0.89[CEU]
rs4614953	downstream_gene_variant	0.936[TSI]
rs4594469		0.857[CEU]
rs3821312	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.934[TSI]
rs3771799	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.902[TSI]
rs2422087		0.857[CEU]; 0.966[TSI]
rs12463607		0.857[CEU]
rs6546948		0.857[CEU]
rs4853094		0.857[CEU]
rs6740220		0.934[TSI]
rs6546944		0.857[CEU]
rs7594760		0.934[TSI]
rs6546947		0.857[CEU]
rs11677184	downstream_gene_variant; upstream_gene_variant	0.934[TSI]
rs7588436		0.857[CEU]
rs7575326		0.857[CEU]; 0.934[TSI]
rs3732303	3_prime_UTR_variant; downstream_gene_variant	0.936[TSI]
rs4853097		0.857[CEU]; 0.967[TSI]
rs4853096		0.857[CEU]
rs4853100		0.934[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)