SNP Report

Basic Info

Name	rs11001178 dbSNP Ensembl
Location	chrCHR_HG2191_PATCH:74844104 - 74844104(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.446286
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000287239, ENST00000372711, ENST00000372714, ENST00000372724, ENST00000372725, ENST00000604130); non_coding_transcript_variant(ENST00000604130, ENST00000627572, ENST00000628038, ENST00000628523, ENST00000629233, ENST00000629879, ENST00000630001, ENST00000627572)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kuo, P. H., 2014			P-value=0.00075,Â OR=0.6, 95%CI=0.5-0.8 for the second stage...... P-value=0.00075,Â OR=0.6, 95%CI=0.5-0.8 for the second stage, combined P-value=0.02 for the replication stage. More...	The marker is identified to be associated with bipolar disor...... The marker is identified to be associated with bipolar disorder in the fine-mapping stage with P-value less than 0.05. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
KAT6B	K(lysine) acetyltransferase 6B	10q22.2	1(1/0/0)

SNPs in LD with rs11001178 (count: 20) View in gBrowse (chrCHR_HG2191_PATCH:74773136..74896880 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs958320	intron_variant	1.0[CHB]; 0.972[CHD]; 1.0[JPT]
rs4746231		0.891[CHB]; 0.944[JPT]
rs7073316	downstream_gene_variant	0.943[CHB]; 0.972[CHD]; 1.0[JPT]
rs1538313		0.891[CHB]; 0.944[CHD]; 0.944[JPT]
rs10824242	intron_variant	1.0[CHB]; 0.944[JPT]
rs12260609	intron_variant	1.0[CHB]; 0.944[JPT]
rs4745758		0.891[CHB]; 0.944[CHD]; 0.944[JPT]
rs7913494		0.891[CHB]; 0.944[JPT]
rs10762644		0.891[CHB]; 0.944[JPT]
rs12251559		0.891[CHB]; 0.944[CHD]; 0.944[JPT]
rs7909056		0.891[CHB]; 0.944[JPT]
rs7906881	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs6480762	intron_variant	1.0[CHB]; 0.939[JPT]
rs4745753		0.891[CHB]; 0.944[JPT]
rs7088463		0.891[CHB]; 0.912[CHD]; 0.944[JPT]
rs3862557		0.891[CHB]; 0.944[JPT]
rs4746237		0.891[CHB]; 0.944[CHD]; 0.944[JPT]
rs10824244	intron_variant	0.943[CHB]; 0.943[JPT]
rs951308	intron_variant	1.0[CHB]; 0.972[CHD]; 0.936[JPT]
rs11001179	downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)