SNP Report

Basic Info

Name	rs10510354 dbSNP Ensembl
Location	chr3:7210503 - 7210503(1)
Variant Alleles	G/C
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.20028
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000357716, ENST00000389335, ENST00000389336, ENST00000435689, ENST00000440923, ENST00000448328, ENST00000467425, ENST00000486284); NMD_transcript_variant(ENST00000389335, ENST00000435689, ENST00000440923, ENST00000467425)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kandaswamy R., 2014	C/G		P-value=0.003 P-value=0.003	Significantly associated with BD. Significantly associated with BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GRM7	glutamate receptor, metabotropic 7	3p26-p25	3(2/1/0)

SNPs in LD with rs10510354 (count: 10) View in gBrowse (chr3:7178151..7217997 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs17825046	intron_variant; NMD_transcript_variant	0.88[CEU]
rs11715681	intron_variant; NMD_transcript_variant	0.847[CEU]
rs12715601	intron_variant; NMD_transcript_variant	0.843[CEU]
rs10510352	intron_variant; NMD_transcript_variant	0.812[CEU]
rs6784192	intron_variant; NMD_transcript_variant	0.822[CEU]
rs7652154	intron_variant; NMD_transcript_variant	0.922[CEU]; 0.92[TSI]
rs870738	intron_variant; NMD_transcript_variant	0.869[TSI]
rs1543146	intron_variant; NMD_transcript_variant	0.922[CEU]
rs6795397	intron_variant; NMD_transcript_variant	0.847[CEU]
rs17825034	intron_variant; NMD_transcript_variant	0.886[CEU]; 0.878[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)