BDgene

SNP Report

Basic Info
Name rs10510354 dbSNP Ensembl
Location chr3:7210503 - 7210503(1)
Variant Alleles G/C
Ancestral Allele G
Minor Allele C
Minor Allele Frequence 0.20028
Functional Annotation intron_variant; NMD_transcript_variant.
Consequence to Transcript intron_variant(ENST00000357716, ENST00000389335, ENST00000389336, ENST00000435689, ENST00000440923, ENST00000448328, ENST00000467425, ENST00000486284); NMD_transcript_variant(ENST00000389335, ENST00000435689, ENST00000440923, ENST00000467425)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kandaswamy R., 2014 C/G P-value=0.003 P-value=0.003 Significantly associated with BD. Significantly associated with BD. Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0)

SNPs in LD with rs10510354 (count: 10) View in gBrowse (chr3:7178151..7217997 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)